The Atlanta Falcons will play the Detroit Lions in London as part of the National Football League's 2014 International Series.
Four other teams will also play in London's Wembley Stadium during the 2014 regular season.
The Jacksonville Jaguars will play the Dallas Cowboys, and the Oakland Raiders will go up against the Miami Dolphins.
Dates and times for all three games will be announced by the NFL at a later date.
Atlanta's trip to the UK will mark the first time in the club's 47-year history that it has played in London.
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